
Rhinoscleroma is also known as WOODY NOSE or Hebra Nose or Balkan leprosy

- First described by Hebrew.
- Termed by Von hebra.
- Chronic granulomatous disease of nose.
Causative agents of Hebra Nose
Kliebseilla Rhinoscleromatis(Firsch bacilli –gram negative diplococci).
Sites of infection
- Nasal cavity:- Inferior turbinate> middle turbinate> anterior wall of nasal septum.
- Nasopharynx.
- Oropharynx.
- Larynx:- subglottic> glottis.
- Trachea(cervical).
- Bronchus

Stages of Disease
- Catarrhal stage:- mucopurulent, foul smelling discharge,occasionally blood tinged – CARPENTER’ S GLUE.
- Atrophic stage:- mucosal atrophy, crustations, pinkish mucosa, Honeycomb color crusting. Diagnosed by Immune Compliment fixation test- Levin test.
- Grannulomatous stage/ nodular:- painless ,non tender,small granulomatous nodules,non ulcerating nodules:-Russel bodies, Mikulicz cells.
- Cicatarisation/ sclerotic/fibrosis/stenosis stage:- Typical histological picture is granulomatous changes in submucosa- TAPIR Nose.